Mild Behavioral Impairment Checklist (MBI-C) 

A rating scale for early signs of dementia.
Tech ID #: 1244.1
A checklist to help clinicians identify changes in a patient’s pattern of behavior that may indicate the onset of dementia.
Validated in multiple observational cohorts internationally.
Over 20 language translations are available, and several others are being validated.
Widely applicable for use in clinical settings or research settings, including clinical trials.


Mild Behavior Impairment (MBI) can be an early manifestation of the dementia process, associating with biomarkers for Alzheimer’s disease and other neurodegenerative conditions, in advance of cognitive decline in some.  

Dr. Zahinoor Ismail at the University of Calgary, together with ISTAART colleagues, created the Mild Behavioral Impairment Checklist (MBI-C). The MBI-C can help clinicians note changes in longstanding patterns of behavior or personality that can be symptoms of incident cognitive decline and dementia. The MBI-C can identify disease severity, with MBI-C scores increasing from subjective cognitive decline to mild cognitive impairment, to dementia. 



  • Clinical trials 
  • Research studies  
  • Clinical diagnosis, treatment, and management 



  • Case ascertainment instrument for Mild Behavioral Impairment, based on the ISTAART-AA diagnostic criteria. 
  • Early identification of patients at risk of developing Alzheimer’s and other dementias . 
  • Designed to be used by family members and caregivers of older adults making it easy to comprehend and apply. 



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